Triamcinolone Acetonide
(in 2 products)

Potential Risk Index®:

ISCE InhaleISCE SwallowISCE ContactISCE Environment
PRI Legend

About:

Triamcinolone Acetonide is the acetonide salt form of triamcinolone , a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone acetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished.
Scientific References:

Safety and Hazards (UN GHS):

1. Harmful if swallowed (H302)
2. May damage fertility or the unborn child (H360)
3. Suspected of damaging fertility or the unborn child (H361)

Potential Health Concerns For:

1. Abnormalities, Drug-Induced (PubMed ID:3193449)
2. Adenoma, Liver Cell (PubMed ID:1411124)
3. Carcinoma, Hepatocellular (PubMed ID:1411124)
4. Craniofacial Abnormalities (PubMed ID:7166596)
5. Dermatitis, Allergic Contact (PubMed ID:2530056)
6. Drug Hypersensitivity (PubMed ID:11526524)
7. Encephalocele (PubMed ID:3193449)
8. Gastrointestinal Hemorrhage (PubMed ID:29222744)
9. Glaucoma (PubMed ID:20172078)
10. Granuloma (PubMed ID:13129887)
11. Hepatomegaly (PubMed ID:29222744)
12. Liver Neoplasms, Experimental (PubMed ID:1411124)
13. Meningocele (PubMed ID:3193449)
14. Nervous System Malformations (PubMed ID:7166596)
15. Ocular Hypertension (PubMed ID:20172078)
16. Orbital Diseases (PubMed ID:13129887)
17. Prenatal Exposure Delayed Effects (PubMed ID:7166596)
18. Sclerosis (PubMed ID:13129887)
19. Skin Diseases (PubMed ID:952530)
20. Telangiectasis (PubMed ID:952530)

Potential Health Benefits For:

1. Asthma (PubMed ID:10071519)
2. Choroidal Neovascularization (PubMed ID:16767378)
3. Diabetic Retinopathy (PubMed ID:15290890)
4. Edema (PubMed ID:7206733)
5. Macular Edema (PubMed ID:13129887)
6. Retinal Neovascularization (PubMed ID:15290890)
7. Rhinitis, Allergic (PubMed ID:113742)
8. Rhinitis, Vasomotor (PubMed ID:113742)
9. Uveitis (PubMed ID:19403113)

User Comments:

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