Toluene-2,5-Diamine; 2,5-Diaminotoluene(in 136 products)
Banned by Gov or classified as a carcinogen by IARC
Banned by Gov or classified as a carcinogen by IARC
Potential Risk Index®:
About:
Functions:
1. Colorant - Pigments or dyes that are added in order to change or enhance the color.
Hair dye substance in oxidative hair dye products
(a) General use
(b) Professional use
For (a) and (b):
After mixing under oxidative conditions the maximum concentration to hair must not exceed 4% calculated as free base.
This is a compound which is or has the potential to be an aniline/toluidine salt. Given that companies are not required to list the related salts of the compound used in their ingredients, in the interest of consumer health and safety, similarly related compounds to those found in banned lists will be rated equivalently.
Recent Findings:
The Hong Kong Consumer Council has labelled toluene-2,5-diamine (PTD) as an "extreme sensitiser" and that even "a small amount of sensitisers could trigger allergic skin reactions in some people" despite complying with concentration standards set in Mainland China and the European Union. It has also stated that "p-Phenylenediamine (PPD), m-Phenylenediamine (MPD) and Toluene-2,5-diamine (PTD) were on the Poisons List of Pharmacy and Poisons Regulations".
EU CosIng Annex III Restriction Information:
Regulation:
(EC) No 344/2013
Annex/Ref#:
III/9a
Product Type, body parts:
Hair dye substance in oxidative hair dye products
(a) General use
(b) Professional use
For (a) and (b):
After mixing under oxidative conditions the maximum concentration to hair must not exceed 4% calculated as free base.
Other:
(a) and (b) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 4% calculated as free base
Wording of conditions of use and warnings:
(a) Hair colorants can cause severe allergic reactions.
Read and follow instructions.
This product is not intended for use on persons under the age of 16.
Temporary "black henna" tattoos may increase your risk of allergy.
Do not colour your hair if:
- you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporay "black henna" tattoo in the past.
Contains phenylenediamines (toluenediamines). Do not use to dye eyelashes or eyebrows.
The mixing ratio is printed on the label
(b) For professional use only
Hair colorants can cause severe allergic reactions.
Read and follow instructions.
This product is not intended for use on persons under the age of 16.
Temporary "black henna" tattoos may increase your risk of allergy.
Do not colour your hair if:
- you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporay "black henna" tattoo in the past.
Contains phenylenediamines (toluenediamines). Wear suitable gloves.
The mixing ratio is printed on the label
SCCS opinions:
1054/06 - Memorandum on Hair Dye Substances and their Skin Sensitising Properties
1084/07 - Opinion on Toluene-2,5-diamine
Scientific References:
1. PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/7252
Regulatory References:
1. EU CosIng Annex II, SUBSTANCES PROHIBITED IN COSMETIC PRODUCTS [2017]
- Ref: II/1144
2. CANADA INGREDIENT HOTLIST, List of Ingredients that are Prohibited for Use in Cosmetic Products [2019]
- Aniline, its salts and, its halogenated and sulfonated derivatives
- Toluidines, their isomers, salts and halogenated and sulfonated derivatives except 4-hydroxy-2-nitro-toluidine and hydroxyethyl-2-nitro-p-toluidine
3. South Korea - Ministry of Food and Drug Safety - Prohibited/Restricted Chemicals
- Ref: 959, 1180
4. CANADA INGREDIENT HOTLIST, List of Ingredients that are Restricted for Use in Cosmetic Products [2019]
- Coal tar dye
5. EU CosIng Annex III, SUBSTANCES WITH RESTRICTIONS IN COSMETIC PRODUCTS [2018]
- Ref: III/9a
6. Argentina Ministerio de Salud - Restricciones
- p-fenilendiaminas sus derivados N-sustituidos y sus sales; derivados N-sustituidos de la o-fenilendiamina
7. EU Scientific Committee on Consumer Safety
8. Hong Kong Consumer Council 2015-2016 Annual Report
- Report: Improving Product Quality and Safety, p26
9. Hong Kong Consumer Council
Safety and Hazards (UN GHS):
1. Toxic if swallowed (H301)
2. Harmful in contact with skin (H312)
3. Causes mild skin irritation (H316)
4. May cause an allergic skin reaction (H317)
5. Causes serious eye irritation (H319)
6. Harmful if inhaled (H332)
7. Suspected of damaging fertility or the unborn child (H361)
8. Causes damage to organs (H370)
9. Causes damage to organs through prolonged or repeated exposure (H373)
10. Toxic to aquatic life with long lasting effects (H411)
Potential Health Concerns For:
1. Dermatitis, Allergic Contact (PubMed ID:11906362)
User Comments:
Submit
