(in 8,798 products)

Potential Risk Index®:

ISCE InhaleISCE SwallowISCE ContactISCE Environment
PRI Legend


1. Binder / Stabilizer - Retains the physical characteristics of food/cosmetics and ensure the mixture remains in an even state.
2. Bulking Agent - Non-nutritious or inactive substances added to increase stability of the mixture.
3. Emulsifier - Allows water and oils to remain mixed together to form an emulsion, such as in mayonnaise, ice cream, and homogenized milk
4. Gelling Agent / Thickener - Increases the viscosity by thickening the liquid to give it more texture
5. Humectant - Binds with water to increase skin hydration. Also enhances water absorption of the skin
6. Sweetener - Sugar substitutes which provides a sweet taste without raising blood sugar levels
Sorbitol is a sugar substitute, it is often used in diet foods (including diet drinks and ice cream), mints, cough syrups, and sugar-free chewing gum. Most sorbitol is made from corn syrup, but it is also found in nature, for example in apples, pears, peaches, and prunes. [1]
Sorbitol often is used in modern cosmetics as a humectant and thickener. It is also used in mouthwash, toothpaste, and also in some cigarettes. [1]
Sorbitol is a sugar alcohol found in fruits and plants with diuretic, laxative, and cathartic properties. Unabsorbed sorbitol retains water in the large intestine through osmotic pressure thereby stimulating peristalsis of the intestine and exerting its diuretic, laxative, and cathartic effect. In addition, sorbitol has one-third fewer calories and 60% of the sweetening activity of sucrose hence is used as a sugar replacement in diabetes. [1]
It is approved to use as food additive in EU and generally recognized as safe food substance in US.
Scientific References:
Regulatory References:
1. US FDA Food Additives Status List [2018]
2. EU Approved Food Additive [2018]
- E420
3. US FDA Generally Recognized As Safe (GRAS) Food Substances (21 CFR 184) [2017]
- § 184.1835 - Sorbitol

Potential Health Concerns For:

1. Charcot-Marie-Tooth Disease (PubMed ID:32367058)
2. Diabetes Complications (PubMed ID:16226225)
3. Diabetic Neuropathies (PubMed ID:1828768)
4. Encephalitis (PubMed ID:6424993)
5. Pain (PubMed ID:3198369)
6. Peripheral Nervous System Diseases (PubMed ID:8483299)

Potential Health Benefits For:

1. Neoplasms (PubMed ID:25557509)
2. Tinea (PubMed ID:25414073)

User Comments:

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