Sodium Nitrite(in 1,010 products)
Potential Risk Index®:
About:
Functions:
1. Preservative - Prevents and inhibits the growth of unwanted microorganisms which may be harmful
Sodium nitrite is a useful precursor to a variety of organic compounds, such as pharmaceuticals, dyes, and pesticides, but it is probably best known as a food additive (E250) to prevent botulism.
Sodium nitrite has been found to inhibit growth of disease-causing microorganisms; give taste and color to the meat; and inhibit lipid oxidation that leads to rancidity. The appearance and taste of meat is an important component of consumer acceptance. Sodium nitrite is responsible for the desirable red color (or shaded pink) of meat. Very little nitrite is needed to induce this change. It has been reported that as little as 2 to 14 parts per million (ppm) is needed to induce this desirable color change. However, to extend the lifespan of this color change, significantly higher levels are needed. [1]
It is approved to use as food additive in EU and US.
EU CosIng Annex III Restriction Information:
Regulation:
(EC) No 1223/2009
Regulated By:
82/368/EEC
Annex/Ref#:
III/17
Product Type, body parts:
Rust inhibitor
Maximum concentration in ready for use preparation:
0.2%
Other:
Not to be used with secondary and/or tertiary amines or other substances forming nitrosamines
Scientific References:
Regulatory References:
1. South Korea - Ministry of Food and Drug Safety - Prohibited/Restricted Chemicals
- Ref: 1252
2. WHO International Agency for Research on Cancer (IARC) - Group 2A [2018]
- Nitrate or nitrite (ingested) under conditions that result in endogenous nitrosation
3. EU CosIng Annex III, SUBSTANCES WITH RESTRICTIONS IN COSMETIC PRODUCTS [2018]
- Ref: III/17
4. Argentina Ministerio de Salud - Restricciones
- Nitrito de sodio
5. US FDA Food Additives Status List [2018]
- Nitrites (sodium and potassium)
6. EU Approved Food Additive [2018]
- E250
7. Japan’s List of Designated Food Additives under Article 10 of the Food Sanitation Act
- Sodium Nitrite
Safety and Hazards (UN GHS):
1. Toxic if swallowed (H301)
2. Causes serious eye irritation (H319)
3. Suspected of causing genetic defects (H341)
4. Suspected of damaging fertility or the unborn child (H361)
5. May cause harm to breast-fed children (H362)
6. Causes damage to organs (H370)
7. Causes damage to organs through prolonged or repeated exposure (H373)
8. Very toxic to aquatic life (H400)
9. Very toxic to aquatic life with long lasting effects (H410)
Potential Health Concerns For:
1. Adenocarcinoma (PubMed ID:7955072)
2. Amnesia (PubMed ID:19345205)
3. Amnesia, Anterograde (PubMed ID:16053272)
4. Chemical and Drug Induced Liver Injury (PubMed ID:28833918)
5. Chromosome Breakage (PubMed ID:31476334)
6. Endometrial Neoplasms (PubMed ID:7955072)
7. Hemangiosarcoma (PubMed ID:168160)
8. Hypotension (PubMed ID:999414)
9. Hypoxia (PubMed ID:2084452)
10. Infant Death (PubMed ID:31476334)
11. Infertility, Female (PubMed ID:31476334)
12. Inflammation (PubMed ID:28000380)
13. Liver Neoplasms, Experimental (PubMed ID:168160)
14. Lung Injury (PubMed ID:28266762)
Potential Health Benefits For:
1. Poisoning (PubMed ID:21534623)
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