Monosodium Glutamate; Sodium Glutamate(in 3,946 products)
Potential Risk Index®:
About:
Functions:
1. Biologics - Biological components such as amino acids and its derivatives which modifies certain functions
2. Dietary / Nutritional Supplement - Vitamins, minerals, proteins, fatty acids or probiotics that improves nutritional intake
3. Flavor / Flavoring / Flavor Enhancer - Provides or enhances a particular taste or smell.
Monosodium Glutamate (MSG) (E621), the sodium salt of glutamic acid, which can be naturally found in tomatoes, cheese and other foods. It is used in the food industry as a flavour enhancer with an umami taste that intensifies the meaty, savory flavor of food, as naturally occurring glutamate does in foods such as stews and meat soups. In Japan, it is commonly used as soup base. [1]
It is approved to use as food additive in EU and generally recognized as safe food substance in US.
Scientific References:
1. PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/167560
Regulatory References:
1. EU Approved Food Additive [2018]
- E621
2. Japan’s List of Designated Food Additives under Article 10 of the Food Sanitation Act
- Monosodium L-Glutamate
3. US FDA Generally Recognized As Safe (GRAS) (21 CFR 182) [2017]
Safety and Hazards (UN GHS):
1. Harmful if swallowed (H302)
2. Harmful in contact with skin (H312)
3. Causes serious eye irritation (H319)
4. Harmful if inhaled (H332)
5. May cause respiratory irritation (H335)
6. Harmful to aquatic life with long lasting effects (H412)
Potential Health Concerns For:
1. Atrophy (PubMed ID:12077204)
2. Brain Injuries (PubMed ID:22447225)
3. Chemical and Drug Induced Liver Injury (PubMed ID:19001666)
4. Cognition Disorders (PubMed ID:22447225)
5. Diabetes Mellitus, Experimental (PubMed ID:21549692)
6. Fatty Liver (PubMed ID:19001666)
7. Feeding and Eating Disorders (PubMed ID:25473020)
8. Gliosis (PubMed ID:20928830)
9. Glucose Intolerance (PubMed ID:18048028)
10. Glycosuria (PubMed ID:21549692)
11. Growth Disorders (PubMed ID:7533119)
12. Hepatomegaly (PubMed ID:19001666)
13. Hypercholesterolemia (PubMed ID:22223845)
14. Hyperglycemia (PubMed ID:20376352)
15. Hyperinsulinism (PubMed ID:21205225)
16. Hyperlipidemias (PubMed ID:21549692)
17. Hypertension (PubMed ID:25211138)
18. Hypertriglyceridemia (PubMed ID:26092479)
19. Hypogonadism (PubMed ID:14657608)
20. Insulin Resistance (PubMed ID:18048028)
21. Metabolic Syndrome X (PubMed ID:21549692)
22. Nerve Degeneration (PubMed ID:12077204)
23. Non-alcoholic Fatty Liver Disease (PubMed ID:21549692)
24. Obesity (PubMed ID:11753755)
25. Optic Nerve Injuries (PubMed ID:12077204)
26. Pre-Eclampsia (PubMed ID:22169520)
27. Prenatal Exposure Delayed Effects (PubMed ID:25697375)
28. Seizures (PubMed ID:16584647)
29. Weight Gain (PubMed ID:15231871)
30. Weight Loss (PubMed ID:19001666)
Potential Health Benefits For:
1. Anorexia (PubMed ID:21824258)
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