Hyaluronic Acid
(in 10,742 products)

Potential Risk Index®:

ISCE InhaleISCE SwallowISCE ContactISCE Environment
PRI Legend


1. Drug / Medicine - Used to treat, alleviate, cure or prevent sickness. As officially declared by a governmental drug/medicine regulatory body
2. Emollient - Softens and soothes the skin. Prevents water (moisture) loss from the skin.
Hyaluronic acid (HA; conjugate base hyaluronate), also called hyaluronan, is a substance that is naturally present in the human body. It is found in the highest concentrations in fluids in the eyes and joints. The hyaluronic acid that is used as medicine is extracted from rooster combs or made by bacteria in the laboratory. (1)
Hyaluronic acid is a common ingredient in skin-care products. It is used as a dermal filler in cosmetic surgery. Some people apply hyaluronic acid to the skin for healing wounds, burns, skin ulcers, and as a moisturizer.
Scientific References:
Regulatory References:
1. US FDA Food Additives Status List [2018]
- Substances Added to Food (formerly EAFUS)

Potential Health Concerns For:

1. Cholestasis (PubMed ID:26325587)
2. Esophageal and Gastric Varices (PubMed ID:17539992)
3. Inflammation (PubMed ID:23692848)
4. Ischemia (PubMed ID:23978416)
5. Liver Cirrhosis (PubMed ID:30097701)
6. Liver Cirrhosis, Alcoholic (PubMed ID:23274713)
7. Neoplasm Metastasis (PubMed ID:23978416)
8. Prostatic Neoplasms (PubMed ID:16864594)
9. Pulmonary Disease, Chronic Obstructive (PubMed ID:25106431)
10. Pulmonary Emphysema (PubMed ID:25106431)
11. Retinal Detachment (PubMed ID:27082295)

Potential Health Benefits For:

1. Cartilage Diseases (PubMed ID:23595953)
2. Chemical and Drug Induced Liver Injury (PubMed ID:18237725)
3. Keratosis, Actinic (PubMed ID:20237495)
4. Wounds and Injuries (PubMed ID:23178681)

User Comments:

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