Folic Acid(in 8,182 products)
Potential Risk Index®:
About:
Functions:
1. Dietary / Nutritional Supplement - Vitamins, minerals, proteins, fatty acids or probiotics that improves nutritional intake
Folate, distinct forms of which are known as folic acid, folacin, and vitamin B9, is one of the B vitamins. Folate naturally occurs in a wide variety of foods, including vegetables (particularly dark green leaf vegetables), fruits and fruit juices, nuts, soybeans, chickpeas, dairy products, poultry and meat, eggs, seafood, grains, and some beers. Avocado, beetroot, spinach, liver, yeast, asparagus, kale, and Brussels sprouts are among the foods with the highest levels of folate. Folate naturally found in food is susceptible to high heat and ultraviolet light, and is soluble in water. It is heat-labile in acidic environments and may also be subject to oxidation
Folate in the form of folic acid is used to treat anemia caused by folic acid deficiency. Folic acid is also used as a supplement by women during pregnancy to prevent neural tube defects (NTD) in the baby. Low levels in early pregnancy are believed to be the cause of more than half of babies born with neural tube defects.
Scientific References:
1. PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/6037
Regulatory References:
1. Japan’s List of Designated Food Additives under Article 10 of the Food Sanitation Act
- Folic Acid
Safety and Hazards (UN GHS):
1. Causes skin irritation (H315)
2. Causes serious eye irritation (H319)
Potential Health Concerns For:
1. Acute Kidney Injury (PubMed ID:1068326)
2. Albuminuria (PubMed ID:22647887)
3. Alzheimer Disease (PubMed ID:15607954)
4. Anemia (PubMed ID:12187553)
5. Anemia, Macrocytic (PubMed ID:1243953)
6. Anemia, Megaloblastic (PubMed ID:14227437)
7. Anuria (PubMed ID:851170)
8. Ataxia (PubMed ID:7442434)
9. Autistic Disorder (PubMed ID:21388746)
10. Birth Weight (PubMed ID:30920123)
11. Brain Diseases (PubMed ID:6824947)
12. Chemical and Drug Induced Liver Injury (PubMed ID:15338491)
13. Cleft Lip (PubMed ID:21254359)
14. Cleft Palate (PubMed ID:21254359)
15. Cognition Disorders (PubMed ID:15824266)
16. Colorectal Neoplasms (PubMed ID:17087956)
17. Coronary Restenosis (PubMed ID:15215483)
18. Dementia (PubMed ID:7527320)
19. Depressive Disorder (PubMed ID:7527320)
20. Diabetes Mellitus, Type 2 (PubMed ID:30153273)
21. Disease Models, Animal (PubMed ID:20406136)
22. Drug-Related Side Effects and Adverse Reactions (PubMed ID:16166815)
23. Epilepsy (PubMed ID:1115018)
24. Exfoliation Syndrome (PubMed ID:16504073)
25. Fetal Alcohol Spectrum Disorders (PubMed ID:22666445)
26. Fibrosis (PubMed ID:29789558)
27. Folic Acid Deficiency (PubMed ID:30153273)
28. Gastritis (PubMed ID:17171786)
29. Genital Diseases, Male (PubMed ID:15013062)
30. Glaucoma (PubMed ID:16504073)
31. Glucose Intolerance (PubMed ID:30153273)
32. HIV Seropositivity (PubMed ID:17209195)
33. Hepatomegaly (PubMed ID:25733650)
34. Hydrocephalus (PubMed ID:14324085)
35. Hyperhomocysteinemia (PubMed ID:15493348)
36. Hypertension (PubMed ID:15190049)
37. Insulin Resistance (PubMed ID:29056104)
38. Kidney Diseases (PubMed ID:11832423)
39. Kidney Failure, Chronic (PubMed ID:4810836)
40. Kidney Tubular Necrosis, Acute (PubMed ID:12969123)
41. Learning Disorders (PubMed ID:30153273)
42. Liver Diseases (PubMed ID:16877991)
43. Lupus Erythematosus, Systemic (PubMed ID:17718048)
44. Memory Disorders (PubMed ID:30153273)
45. Neoplasms (PubMed ID:6061664)
46. Nephritis, Interstitial (PubMed ID:15013062)
47. Nervous System Diseases (PubMed ID:5343988)
48. Neural Tube Defects (PubMed ID:10452927)
49. Non-alcoholic Fatty Liver Disease (PubMed ID:20548288)
50. Obesity (PubMed ID:30153273)
51. Peripheral Nervous System Diseases (PubMed ID:7527320)
52. Prenatal Exposure Delayed Effects (PubMed ID:29546377)
53. Prenatal Injuries (PubMed ID:20544798)
54. Proteinuria (PubMed ID:20116427)
55. Psychotic Disorders (PubMed ID:25729574)
56. Renal Insufficiency (PubMed ID:14661866)
57. Renal Insufficiency, Chronic (PubMed ID:29380373)
58. Schizophrenia (PubMed ID:25729574)
59. Seizures (PubMed ID:1463588)
60. Skin Diseases (PubMed ID:19270796)
61. Spinal Cord Diseases (PubMed ID:7527320)
62. Spinal Dysraphism (PubMed ID:20544798)
63. Splenomegaly (PubMed ID:25733650)
64. Stomach Neoplasms (PubMed ID:17171786)
65. Uremia (PubMed ID:4082191)
Potential Health Benefits For:
1. Abnormalities, Drug-Induced (PubMed ID:11096168)
2. Adenoma (PubMed ID:16963246)
3. Ageusia (PubMed ID:3214955)
4. Alcohol Withdrawal Delirium (PubMed ID:7220787)
5. Anemia, Aplastic (PubMed ID:12028229)
6. Anemia, Hemolytic (PubMed ID:5774135)
7. Anemia, Hemolytic, Autoimmune (PubMed ID:5694067)
8. Anemia, Sickle Cell (PubMed ID:18593679)
9. Anemia, Sideroblastic (PubMed ID:7986730)
10. Anencephaly (PubMed ID:12397633)
11. Arteriosclerosis (PubMed ID:17118406)
12. Arthritis, Psoriatic (PubMed ID:17190135)
13. Atrophy (PubMed ID:23690582)
14. Bipolar Disorder (PubMed ID:20636639)
15. Brain Damage, Chronic (PubMed ID:23690582)
16. Breast Neoplasms (PubMed ID:16777985)
17. Carcinoma, Renal Cell (PubMed ID:10663624)
18. Cardiomyopathies (PubMed ID:29068127)
19. Cardiovascular Abnormalities (PubMed ID:11096168)
20. Cardiovascular Diseases (PubMed ID:16755160)
21. Cataract (PubMed ID:11438049)
22. Cerebellar Ataxia (PubMed ID:4022349)
23. Color Vision Defects (PubMed ID:15937433)
24. Congenital Abnormalities (PubMed ID:11096168)
25. Dizziness (PubMed ID:3214955)
26. Embryo Loss (PubMed ID:26993217)
27. Endometrial Neoplasms (PubMed ID:17301261)
28. Fatty Liver, Alcoholic (PubMed ID:20118189)
29. Fetal Growth Retardation (PubMed ID:24177262)
30. Headache (PubMed ID:3214955)
31. Heart Defects, Congenital (PubMed ID:16524890)
32. Hematologic Diseases (PubMed ID:2891393)
33. Hypercholesterolemia (PubMed ID:26400185)
34. Hyperglycemia (PubMed ID:26400185)
35. Hyperkinesis (PubMed ID:20636639)
36. Hypospadias (PubMed ID:19270804)
37. Liver Cirrhosis (PubMed ID:23374533)
38. Malaria, Falciparum (PubMed ID:4922770)
39. Maxillofacial Abnormalities (PubMed ID:16832597)
40. Melanoma (PubMed ID:10663624)
41. Meningomyelocele (PubMed ID:25885259)
42. Mucositis (PubMed ID:8958188)
43. Muscular Diseases (PubMed ID:4148461)
44. Nasopharyngeal Neoplasms (PubMed ID:21941485)
45. Neoplasms, Experimental (PubMed ID:10449194)
46. Neutropenia (PubMed ID:16322990)
47. Optic Nerve Diseases (PubMed ID:15937433)
48. Osteomalacia (PubMed ID:4148461)
49. Placenta Diseases (PubMed ID:29129240)
50. Polycystic Ovary Syndrome (PubMed ID:26545973)
51. Psoriasis (PubMed ID:15807694)
52. Psychophysiologic Disorders (PubMed ID:4169978)
53. Scotoma (PubMed ID:15937433)
54. Sinus Thrombosis, Intracranial (PubMed ID:18786290)
55. Sprue, Tropical (PubMed ID:4951496)
56. Stroke (PubMed ID:16517955)
57. Teratogenesis (PubMed ID:19091803)
58. Thrombocytopenia (PubMed ID:8958188)
59. Toxoplasmosis (PubMed ID:8228015)
60. Ventricular Dysfunction (PubMed ID:28608983)
61. Ventricular Remodeling (PubMed ID:28608983)
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