EDTA; Edetic Acid
(in 1,074 products)

Potential Risk Index®:

ISCE InhaleISCE SwallowISCE ContactISCE Environment
PRI Legend

About:

Functions:
1. Antioxidant - Reduces oxidation to prevent the formation of free radicals which may be harmful to health.
2. Chelating Agent (Chelants) - Binds to and removes potentially toxic or unwanted metals
3. Drug / Medicine - Treats, alleviates, cures, or prevents sickness. As officially declared by a governmental drug/medicine regulatory body
4. Preservative - Prevents and inhibits the growth of unwanted microorganisms which may be harmful
Edetate calcium is a heavy metal chelating agent. The calcium in edetate calcium can be displaced by divalent or trivalent metals to form a stable water soluble complex that can be excreted in the urine. In theory, 1 g of edetate calcium can theoretically bind 620 mg of lead, but in reality only about 5 mg per gram is actually excreted into the urine in lead poisoned patients. In addition to chelating lead, edetate calcium also chelates and eliminates zinc from the body. Edetate calcium also binds cadmium , copper , iron and manganese , but to a much lesser extent than either lead or zinc . Edetate calcium is relatively ineffective for use in treating mercury , gold or arsenic poisoning. Edetic Acid is the acid form of edetate , a chelating agent with anti-hypercalcemic and anticoagulant properties. Edetic acid binds calcium and heavy metal ions, forming soluble stable complexes which are readily excreted by the kidneys. This results in a decrease in serum calcium levels. This agent is also used as an anticoagulant for blood specimens and is applied as a treatment of lead poisoning. [1]
Scientific References:

Safety and Hazards (UN GHS):

1. Harmful if swallowed (H302)
2. Harmful in contact with skin (H312)
3. Causes skin irritation (H315)
4. Causes serious eye irritation (H319)
5. Harmful if inhaled (H332)
6. May cause respiratory irritation (H335)
7. Suspected of damaging fertility or the unborn child (H361)
8. Causes damage to organs through prolonged or repeated exposure (H372)
9. Causes damage to organs through prolonged or repeated exposure (H373)
10. Harmful to aquatic life (H402)
11. Harmful to aquatic life with long lasting effects (H412)

Potential Health Concerns For:

1. Acute Kidney Injury (PubMed ID:6424257)
2. Anemia, Hemolytic, Autoimmune (PubMed ID:6417354)
3. Back Pain (PubMed ID:2138439)
4. Chromosome Aberrations (PubMed ID:16406784)
5. Drug Eruptions (PubMed ID:9452326)
6. Drug-Related Side Effects and Adverse Reactions (PubMed ID:8452485)
7. Extravasation of Diagnostic and Therapeutic Materials (PubMed ID:7706905)
8. Hyperplasia (PubMed ID:3142305)
9. Hypocalcemia (PubMed ID:3103339)
10. Nephrosis (PubMed ID:4982032)
11. Nervous System Neoplasms (PubMed ID:3142305)
12. Pain (PubMed ID:10499828)
13. Vasculitis (PubMed ID:6417354)
14. Vasculitis, Leukocytoclastic, Cutaneous (PubMed ID:9452326)
15. Ventricular Fibrillation (PubMed ID:4066228)

Potential Health Benefits For:

1. Dystonia (PubMed ID:22926781)
2. Hemorrhage (PubMed ID:28245079)
3. Hypermanganesemia with Dystonia Polycythemia and Cirrhosis (PubMed ID:22341971)
4. Lead Poisoning (PubMed ID:125923)
5. Necrosis (PubMed ID:26908177)
6. Nerve Degeneration (PubMed ID:33400970)
7. Nervous System Diseases (PubMed ID:14732471)
8. Neurotoxicity Syndromes (PubMed ID:20306169)

User Comments:

Subtotal: $0.00 HKD