Dibutyl Phthalate(in 66 products)
Banned by Gov or classified as a carcinogen by IARC
Banned by Gov or classified as a carcinogen by IARC
Potential Risk Index®:
About:
Functions:
1. Plasticizer (Cosmetics) - Softens polymers by reducing brittleness and cracking
Dibutyl phthalate is used to help make plastics soft and flexible. It is used in shower curtains, raincoats, food wraps, bowls, car interiors, vinyl fabrics, floor tiles, and other products. [1]
This substance has been prohibited by the European Commission for use in cosmetic products.
Scientific References:
1. PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/3026
Regulatory References:
1. EU CosIng Annex II, SUBSTANCES PROHIBITED IN COSMETIC PRODUCTS [2017]
- Ref: II/675
2. Association of Southeast Asian Nations Annex II, Prohibited
- Dibutyl phthalate
3. US California Assembly Bill 2762, Banned Ingredients in Cosmetic Products
- Dibutyl phthalate
4. South Korea - Ministry of Food and Drug Safety - Prohibited/Restricted Chemicals
- Ref: 671
5. US California Proposition 65, Chemicals known to the State to Cause Developmental or Reproductive Toxicity in Males
- Di-n-butyl phthalate (DBP)
6. US California Proposition 65, Chemicals known to the State to Cause Developmental or Reproductive Toxicity in Females
- Di-n-butyl phthalate (DBP)
7. US CARB Identified Toxic Air Contaminants
- Dibutylphthalate
8. FDA Approved
- dibutylphthalate (DBP)
9. Cosmetic Ingredient Review
- Dibutyl Phthalate
Safety and Hazards (UN GHS):
1. May cause an allergic skin reaction (H317)
2. May cause respiratory irritation (H335)
3. May damage fertility or the unborn child (H360)
4. May damage the unborn child; Suspected of damaging fertility (H360Df)
5. Causes damage to organs through prolonged or repeated exposure (H372)
6. Very toxic to aquatic life (H400)
7. Toxic to aquatic life with long lasting effects (H411)
Potential Health Concerns For:
1. Abnormalities, Drug-Induced (PubMed ID:22027561)
2. Abnormalities, Multiple (PubMed ID:22975441)
3. Aneuploidy (PubMed ID:30763314)
4. Anorectal Malformations (PubMed ID:25213187)
5. Asthenozoospermia (PubMed ID:22489061)
6. Atrophy (PubMed ID:26804720)
7. Birth Weight (PubMed ID:27352641)
8. Brain Injuries (PubMed ID:30776390)
9. Chemical and Drug Induced Liver Injury (PubMed ID:33508418)
10. Cryptorchidism (PubMed ID:16037377)
11. Dermatitis, Contact (PubMed ID:29198882)
12. Diabetes Mellitus, Experimental (PubMed ID:29526571)
13. Diabetes Mellitus, Type 2 (PubMed ID:29526571)
14. Digestive System Abnormalities (PubMed ID:22027561)
15. Disease Models, Animal (PubMed ID:19464577)
16. Disorders of Sex Development (PubMed ID:17361019)
17. Fetal Death (PubMed ID:32860865)
18. Fetal Weight (PubMed ID:32860865)
19. Fibrosis (PubMed ID:32860865)
20. Genital Diseases, Female (PubMed ID:30940548)
21. Genital Diseases, Male (PubMed ID:15013062)
22. Genitourinary Tract Anomalies (PubMed ID:33086118)
23. Glucose Intolerance (PubMed ID:29526571)
24. Gonadal Dysgenesis (PubMed ID:33086118)
25. Hematologic Diseases (PubMed ID:31979393)
26. Hepatomegaly (PubMed ID:31979393)
27. Hyperglycemia (PubMed ID:29526571)
28. Hyperkinesis (PubMed ID:26108271)
29. Hyperplasia (PubMed ID:24067674)
30. Hypospadias (PubMed ID:17400582)
31. Infertility (PubMed ID:30763314)
32. Infertility, Male (PubMed ID:24973093)
33. Insulin Resistance (PubMed ID:29526571)
34. Kidney Diseases (PubMed ID:23359474)
35. Megacolon (PubMed ID:22027561)
36. Movement Disorders (PubMed ID:27029555)
37. Neoplasm Metastasis (PubMed ID:22552774)
38. Nephrosclerosis (PubMed ID:28919491)
39. Oligospermia (PubMed ID:22489061)
40. Ovarian Diseases (PubMed ID:23359474)
41. Pancreatic Diseases (PubMed ID:29526571)
42. Poisoning (PubMed ID:22975441)
43. Pregnancy, Prolonged (PubMed ID:19464577)
44. Premature Birth (PubMed ID:24503621)
45. Prenatal Exposure Delayed Effects (PubMed ID:19010379)
46. Prenatal Injuries (PubMed ID:28067064)
47. Prostatic Diseases (PubMed ID:23359474)
48. Puberty, Precocious (PubMed ID:34280466)
49. Splenic Diseases (PubMed ID:31712109)
50. Teratozoospermia (PubMed ID:34280466)
51. Testicular Diseases (PubMed ID:17400582)
52. Weight Gain (PubMed ID:29029336)
53. Weight Loss (PubMed ID:19464577)
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