Diazolidinylurea

(in 13,828 products)

1. Antimicrobial Preservative - Actively kills and inhibits the growth of unwanted microorganisms which may be harmful.

2. Drug / Medicine - Treats, alleviates, cures, or prevents sickness. As officially declared by a governmental drug/medicine regulatory body

3. Preservative - Prevents and inhibits the growth of unwanted microorganisms which may be harmful

May release Formaldehyde under aqueous conditions, such as contacting with water or in humid conditions.[2]

Please see 'Formaldehyde' for further details.

- 150ppm of formaldehyde can be recovered from shampoos using 0.1% diazolidinylurea and up to 740ppm can be recovered from a concentration of 0.8%. In protein-based shampoos, the formaldehyde recovered is lower as formaldehyde can be complexed (binded) to the protein, preventing its release.

- As for environmental impacts, diazolidinylurea can also be used to promote tissue healing in "salt water, tropical, and cold water fish". [3]

- In a separate study, diazolidinylurea has proven its effectiveness as an anti-fungal and anti-bacterial agent, especially when combined with other antimicrobial compounds such as N-chloramines and parabens. [4]

1. PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/62277

2. Investigation on formaldehyde release from preservatives in cosmetics (Int J Cosmet Sci. 2015 Oct;37(5):474-8. doi: 10.1111/ics.12212)

3. Final Report on the Safety Assessment of Diazolidinyl Urea (Int. J. Toxicol. 1990 March;9(2):229-245. doi: 10.3109/10915819009078735)

4. Antimicrobial Activities of N-Chloramines and Diazolidinyl Urea (Appl. Environ. Microbiol. Feb 1985, 49 (2) 370-373)

1. South Korea - Ministry of Food and Drug Safety - Prohibited/Restricted Chemicals

- Ref: 665

2. Cosmetic Ingredient Review

- Diazolidinyl Urea

3. Hong Kong Consumer Council

- Diazolidinyl Urea - Formaldehyde Releaser

4. EU CosIng Annex V, PRESERVATIVES ALLOWED IN COSMETIC PRODUCTS [2017]

- Ref: V/46