BPA; Bisphenol A
(in 0 products)
Banned by Gov or classified as a carcinogen by IARC

Potential Risk Index®:

ISCE InhaleISCE SwallowISCE ContactISCE Environment
PRI Legend


Bisphenol A appears as white to light brown flakes or powder. It has a weak medicine odor. It has a role as a xenoestrogen, an environmental contaminant, a xenobiotic and an endocrine disruptor. [1] Bisphenol A is used as a plastic precursor and is needed to synthesize certain types of plastics.
This substance has been prohibited by the European Commission for use in cosmetic products.
Scientific References:
Regulatory References:
- Ref: II/1176
2. CANADA INGREDIENT HOTLIST, List of Ingredients that are Prohibited for Use in Cosmetic Products [2019]
- 4,4'-Isopropylidenediphenol
3. US California Proposition 65, Chemicals known to the State to Cause Developmental or Reproductive Toxicity in Females
- Bisphenol A (BPA)

Safety and Hazards (UN GHS):

1. May cause an allergic skin reaction (H317)
2. Causes serious eye damage (H318)
3. May cause respiratory irritation (H335)
4. May cause drowsiness or dizziness (H336)
5. May damage fertility or the unborn child (H360)
6. May damage fertility (H360F)
7. Suspected of damaging fertility or the unborn child (H361)
8. Suspected of damaging fertility (H361f)
9. Causes damage to organs (H370)
10. Causes damage to organs through prolonged or repeated exposure (H373)
11. Toxic to aquatic life (H401)
12. Toxic to aquatic life with long lasting effects (H411)
13. Harmful to aquatic life with long lasting effects (H412)

Potential Health Concerns For:

1. Abnormalities, Drug-Induced (PubMed ID:20299547)
2. Abnormalities, Multiple (PubMed ID:23637088)
3. Acute Kidney Injury (PubMed ID:24625398)
4. Adenocarcinoma (PubMed ID:19590677)
5. Albuminuria (PubMed ID:22398408)
6. Aneuploidy (PubMed ID:18225860)
7. Angina Pectoris (PubMed ID:20084273)
8. Anxiety Disorders (PubMed ID:22957036)
9. Arrest of spermatogenesis (PubMed ID:25181051)
10. Arrhythmias, Cardiac (PubMed ID:21980463)
11. Asthenozoospermia (PubMed ID:25461564)
12. Asthma (PubMed ID:31906378)
13. Atherosclerosis (PubMed ID:21621210)
14. Atrophy (PubMed ID:21536718)
15. Attention Deficit Disorder with Hyperactivity (PubMed ID:21277317)
16. Attention Deficit and Disruptive Behavior Disorders (PubMed ID:25307304)
17. Autism Spectrum Disorder (PubMed ID:25641946)
18. Autoimmune Diseases (PubMed ID:27869686)
19. Birth Weight (PubMed ID:22050967)
20. Body Weight (PubMed ID:24705360)
21. Body Weight Changes (PubMed ID:24496637)
22. Bone Diseases, Developmental (PubMed ID:29732168)
23. Bradycardia (PubMed ID:27486708)
24. Brain Injuries (PubMed ID:30997025)
25. Breast Neoplasms (PubMed ID:17123778)
26. Bronchial Hyperreactivity (PubMed ID:20123615)
27. Camptocormia (PubMed ID:30075455)
28. Carcinoma in Situ (PubMed ID:17123778)
29. Carcinoma, Ductal, Breast (PubMed ID:24988533)
30. Cardiomegaly (PubMed ID:25594700)
31. Cardiomyopathy, Dilated (PubMed ID:25996886)
32. Cardiomyopathy, Hypertrophic (PubMed ID:25572651)
33. Cardiovascular Diseases (PubMed ID:32804211)
34. Carotid Stenosis (PubMed ID:21621210)
35. Cell Transformation, Neoplastic (PubMed ID:26546977)
36. Chemical and Drug Induced Liver Injury (PubMed ID:24625398)
37. Child Behavior Disorders (PubMed ID:22707478)
38. Chromosome Aberrations (PubMed ID:21059909)
39. Chromosome Breakage (PubMed ID:25933419)
40. Cognition Disorders (PubMed ID:20169576)
41. Colonic Diseases (PubMed ID:31394344)
42. Conduct Disorder (PubMed ID:25307304)
43. Congenital Abnormalities (PubMed ID:29161229)
44. Congenital, Hereditary, and Neonatal Diseases and Abnormalities (PubMed ID:27841950)
45. Coronary Artery Disease (PubMed ID:22354940)
46. Coronary Disease (PubMed ID:20084273)
47. Craniofacial Abnormalities (PubMed ID:22194820)
48. Cystadenoma (PubMed ID:19590677)
49. Cysts (PubMed ID:20413367)
50. Death (PubMed ID:32804211)
51. Demyelinating Diseases (PubMed ID:24191696)
52. Dental Enamel Hypoplasia (PubMed ID:23764278)
53. Depressive Disorder (PubMed ID:23240141)
54. Diabetes Mellitus (PubMed ID:20084273)
55. Diabetes Mellitus, Type 1 (PubMed ID:24189131)
56. Diabetes Mellitus, Type 2 (PubMed ID:22046388)
57. Digestive System Abnormalities (PubMed ID:23637088)
58. Disease Models, Animal (PubMed ID:23764278)
59. Disease Progression (PubMed ID:23810794)
60. Drug Hypersensitivity (PubMed ID:22446810)
61. Dyslipidemias (PubMed ID:27502578)
62. Edema (PubMed ID:15364205)
63. Edema, Cardiac (PubMed ID:26322593)
64. Embryo Loss (PubMed ID:23653003)
65. Endometrial Hyperplasia (PubMed ID:28959593)
66. Endometriosis (PubMed ID:25205760)
67. Erectile Dysfunction (PubMed ID:19906654)
68. Eye Abnormalities (PubMed ID:19218331)
69. Fatty Liver (PubMed ID:24768697)
70. Feminization (PubMed ID:22692143)
71. Fetal Death (PubMed ID:24576723)
72. Fetal Growth Retardation (PubMed ID:27623287)
73. Fetal Weight (PubMed ID:24496637)
74. Fibrosis (PubMed ID:27025157)
75. Fluorosis, Dental (PubMed ID:27257137)
76. Genital Diseases, Female (PubMed ID:20350546)
77. Gestational Weight Gain (PubMed ID:31864031)
78. Gliosis (PubMed ID:30997025)
79. Glucose Intolerance (PubMed ID:20488778)
80. Glucose Metabolism Disorders (PubMed ID:23493373)
81. Gonadal Disorders (PubMed ID:19479018)
82. Heart Defects, Congenital (PubMed ID:22194820)
83. Heart Diseases (PubMed ID:27025157)
84. Heart Injuries (PubMed ID:30496632)
85. Hematologic Diseases (PubMed ID:31979393)
86. Hemorrhage (PubMed ID:20728951)
87. Hepatomegaly (PubMed ID:25112833)
88. Hyperalgesia (PubMed ID:31574244)
89. Hypercholesterolemia (PubMed ID:25168180)
90. Hyperemia (PubMed ID:29558425)
91. Hyperglycemia (PubMed ID:24705360)
92. Hyperinsulinism (PubMed ID:27145005)
93. Hyperkinesis (PubMed ID:22108044)
94. Hyperplasia (PubMed ID:18938238)
95. Hyperprolactinemia (PubMed ID:11108262)
96. Hypertension (PubMed ID:22363351)
97. Hypertension, Pregnancy-Induced (PubMed ID:30303745)
98. Hypertrophy (PubMed ID:18445619)
99. Hypogonadism (PubMed ID:24134786)
100. Hypospadias (PubMed ID:25434310)
101. Hypotension (PubMed ID:25594700)
102. Immunologic Deficiency Syndromes (PubMed ID:29195089)
103. Infant Death (PubMed ID:28393075)
104. Infertility (PubMed ID:21059909)
105. Infertility, Female (PubMed ID:20413367)
106. Infertility, Male (PubMed ID:12148547)
107. Inflammation (PubMed ID:20018722)
108. Inflammatory Breast Neoplasms (PubMed ID:28426875)
109. Insulin Resistance (PubMed ID:16393666)
110. Kidney Diseases (PubMed ID:18445619)
111. Learning Disorders (PubMed ID:20206181)
112. Liver Cirrhosis, Experimental (PubMed ID:27925325)
113. Liver Neoplasms (PubMed ID:24487385)
114. Liver Neoplasms, Experimental (PubMed ID:27334623)
115. Lung Injury (PubMed ID:30997025)
116. Lung Neoplasms (PubMed ID:27506545)
117. Lymphatic Metastasis (PubMed ID:31143956)
118. Mammary Neoplasms, Animal (PubMed ID:20675265)
119. Mammary Neoplasms, Experimental (PubMed ID:22649256)
120. Memory Disorders (PubMed ID:17467901)
121. Mental Disorders (PubMed ID:23716699)
122. Metabolic Diseases (PubMed ID:24793377)
123. Microcephaly (PubMed ID:15364205)
124. Micronuclei, Chromosome-Defective (PubMed ID:23142537)
125. Migraine Disorders (PubMed ID:24189132)
126. Mood Disorders (PubMed ID:29778459)
127. Motor Skills Disorders (PubMed ID:31574244)
128. Musculoskeletal Abnormalities (PubMed ID:26712470)
129. Myocardial Infarction (PubMed ID:20084273)
130. Myocarditis (PubMed ID:22718145)
131. Myoma (PubMed ID:23915859)
132. Necrosis (PubMed ID:17493787)
133. Neoplasm Invasiveness (PubMed ID:25312822)
134. Neoplasm Metastasis (PubMed ID:21988766)
135. Neoplasms (PubMed ID:32804211)
136. Neoplasms, Experimental (PubMed ID:24424067)
137. Nerve Degeneration (PubMed ID:25381574)
138. Nervous System Malformations (PubMed ID:11399458)
139. Neurobehavioral Manifestations (PubMed ID:24953688)
140. Neuroblastoma (PubMed ID:27366082)
141. Neurologic Manifestations (PubMed ID:20049216)
142. Neurotoxicity Syndromes (PubMed ID:29782159)
143. Non-alcoholic Fatty Liver Disease (PubMed ID:28483554)
144. Obesity (PubMed ID:21676388)
145. Obesity, Abdominal (PubMed ID:21676388)
146. Oligospermia (PubMed ID:19782717)
147. Osteosarcoma (PubMed ID:23886186)
148. Ovarian Cysts (PubMed ID:19590677)
149. Ovarian Diseases (PubMed ID:22187349)
150. Ovarian Neoplasms (PubMed ID:19590677)
151. Overweight (PubMed ID:23776476)
152. Pancreatic Diseases (PubMed ID:32701268)
153. Pericarditis (PubMed ID:31551929)
154. Peripheral Arterial Disease (PubMed ID:22645278)
155. Pigmentation Disorders (PubMed ID:19218331)
156. Pituitary Diseases (PubMed ID:19479018)
157. Placenta Diseases (PubMed ID:29129240)
158. Plaque, Atherosclerotic (PubMed ID:21621210)
159. Pneumonia (PubMed ID:28285737)
160. Poisoning (PubMed ID:27750016)
161. Pre-Eclampsia (PubMed ID:27177253)
162. Precancerous Conditions (PubMed ID:26898831)
163. Premature Birth (PubMed ID:23545179)
164. Prenatal Exposure Delayed Effects (PubMed ID:10188188)
165. Prenatal Injuries (PubMed ID:22426297)
166. Prolactinoma (PubMed ID:27830003)
167. Prostatic Diseases (PubMed ID:15867144)
168. Prostatic Hyperplasia (PubMed ID:26260748)
169. Prostatic Intraepithelial Neoplasia (PubMed ID:20887781)
170. Prostatic Neoplasms (PubMed ID:16740699)
171. Prostatitis (PubMed ID:26260748)
172. Proteinuria (PubMed ID:24809654)
173. Psychomotor Agitation (PubMed ID:25074486)
174. Puberty, Delayed (PubMed ID:28487351)
175. Puberty, Precocious (PubMed ID:10548101)
176. Pulmonary Edema (PubMed ID:30997025)
177. Pulmonary Fibrosis (PubMed ID:28285737)
178. Purpura (PubMed ID:29558425)
179. Sarcoma (PubMed ID:19590677)
180. Scoliosis (PubMed ID:19218331)
181. Somatosensory Disorders (PubMed ID:22194820)
182. Substance-Related Disorders (PubMed ID:16045194)
183. Tauopathies (PubMed ID:32278051)
184. Teratogenesis (PubMed ID:29016128)
185. Teratozoospermia (PubMed ID:30275377)
186. Testicular Diseases (PubMed ID:19193734)
187. Thyroid Diseases (PubMed ID:30352396)
188. Thyroid Neoplasms (PubMed ID:29050248)
189. Urethral Stricture (PubMed ID:15867144)
190. Urogenital Abnormalities (PubMed ID:10806412)
191. Uterine Anomalies (PubMed ID:25666754)
192. Uterine Cervical Neoplasms (PubMed ID:19590677)
193. Uterine Diseases (PubMed ID:14652134)
194. Uterine Neoplasms (PubMed ID:23915859)
195. Vascular Diseases (PubMed ID:24305612)
196. Vascular Malformations (PubMed ID:22194820)
197. Ventricular Premature Complexes (PubMed ID:25723814)
198. Vestibular Diseases (PubMed ID:21269433)
199. Weight Gain (PubMed ID:20019905)
200. Weight Loss (PubMed ID:24134786)

Potential Health Benefits For:

1. Bone Resorption (PubMed ID:11985600)
2. Hyperphagia (PubMed ID:27809950)
3. Hypertrophy, Left Ventricular (PubMed ID:27809950)
4. Parasitic Diseases, Animal (PubMed ID:31291264)

User Comments:

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