Benzoyl Peroxide(in 135 products)
Potential Risk Index®:
About:
Functions:
1. Drug / Medicine - Treats, alleviates, cures, or prevents sickness. As officially declared by a governmental drug/medicine regulatory body
Benzoyl Peroxide is a peroxide with antibacterial, irritant, keratolytic, comedolytic, and anti-inflammatory activity. Upon topical application, benzoyl peroxide decomposes to release oxygen which is lethal to the bacteria Proprionibacterium acnes. Due to its irritant effect, benzoyl peroxide increases turnover rate of epithelial cells, thereby peeling the skin and promoting the resolution of comedones. Benzoyl peroxide is used in the treatment of acne vulgaris.
EU CosIng Annex III Restriction Information:
Regulation:
(EC) No 1223/2009
Regulated By:
2003/83/EC
Annex/Ref#:
III/94
Product Type, body parts:
Artificial nail systems
Maximum concentration in ready for use preparation:
0.7% (after mixing for use)
Other:
Professional use
Wording of conditions of use and warnings:
For professional use only
Avoid skin contact
Read directions for use carefully
SCCS opinions:
0486/01 - Opinion on The Use of Benzoyl Peroxide (BPO), Hydroquinone (HQ), Hydroquinone methylether (MEHQ) in artificial nail systems
Scientific References:
1. PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/7187
Regulatory References:
1. South Korea - Ministry of Food and Drug Safety - Prohibited/Restricted Chemicals
- Ref: 494
2. CANADA INGREDIENT HOTLIST, List of Ingredients that are Restricted for Use in Cosmetic Products [2019]
- Benzoyl peroxide
3. EU CosIng Annex III, SUBSTANCES WITH RESTRICTIONS IN COSMETIC PRODUCTS [2018]
- Ref: III/94
4. E-numbers which are not found in EU FOOD
5. Japan’s List of Designated Food Additives under Article 10 of the Food Sanitation Act
- Benzoyl Peroxide
6. Canada List of Permitted Food Additives
- List 8 - Benzoyl Peroxide
7. WHO Model List of Essential Medicines [2019]
- benzoyl peroxide
8. US FDA Generally Recognized As Safe (GRAS) Food Substances (21 CFR 184) [2017]
- § 184.1157 - Benzoyl peroxide
Safety and Hazards (UN GHS):
1. May cause an allergic skin reaction (H317)
2. Causes serious eye irritation (H319)
3. May cause respiratory irritation (H335)
4. Very toxic to aquatic life (H400)
Potential Health Concerns For:
1. Dermatitis, Allergic Contact (PubMed ID:26795242)
2. Edema (PubMed ID:10753220)
3. Hearing Loss, Sensorineural (PubMed ID:16631957)
4. Hyperplasia (PubMed ID:1923905)
5. Mouth Neoplasms (PubMed ID:1354260)
6. Neoplasms (PubMed ID:15629248)
7. Papilloma (PubMed ID:12065085)
8. Skin Neoplasms (PubMed ID:10753220)
9. Tinnitus (PubMed ID:16631957)
Potential Health Benefits For:
1. Acne Vulgaris (PubMed ID:11522381)
2. Acneiform Eruptions (PubMed ID:17641540)
3. Headache (PubMed ID:16631957)
4. Pressure Ulcer (PubMed ID:6833534)
5. Skin Diseases (PubMed ID:16800173)
6. Skin Ulcer (PubMed ID:6833534)
7. Wound Infection (PubMed ID:6833534)
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