Vitamin B12; Vitamin B 12(in 3,750 products)
Potential Risk Index®:
About:
Functions:
1. Dietary / Nutritional Supplement - Vitamins, minerals, proteins, fatty acids or probiotics that improves nutritional intake
Cyanocobalamin ( Vitamin B12 ) is a water -soluble organometallic compound with a trivalent cobalt ion bound inside a corrin ring. It is needed for nerve cells and red blood cells, and to make DNA. Vitamin B12 deficiency is the cause of several forms of anemia. Cyanocobalamin is a cobalt -containing coordination compound generated by intestinal microbes, and a natural water -soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intestine. Cyanocobalamin is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid . Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.
Scientific References:
Regulatory References:
1. US FDA Generally Recognized As Safe (GRAS) Food Substances (21 CFR 184) [2017]
- § 184.1945 - Vitamin B
Safety and Hazards (UN GHS):
1. Causes skin irritation (H315)
2. Causes serious eye irritation (H319)
Potential Health Concerns For:
1. Adenocarcinoma of Lung (PubMed ID:30499135)
2. Agranulocytosis (PubMed ID:6533326)
3. Alzheimer Disease (PubMed ID:15607954)
4. Anaphylaxis (PubMed ID:5572387)
5. Anemia (PubMed ID:11979747)
6. Anemia, Megaloblastic (PubMed ID:19556642)
7. Anemia, Pernicious (PubMed ID:9314271)
8. Aphonia (PubMed ID:5572387)
9. Ascites (PubMed ID:199903)
10. Autistic Disorder (PubMed ID:16297937)
11. Brain Diseases, Metabolic (PubMed ID:6965256)
12. Bronchial Spasm (PubMed ID:5572387)
13. Carcinoma 256, Walker (PubMed ID:199903)
14. Carcinoma, Small Cell (PubMed ID:30499135)
15. Celiac Disease (PubMed ID:11943958)
16. Central Nervous System Diseases (PubMed ID:9658486)
17. Chemical and Drug Induced Liver Injury (PubMed ID:22166485)
18. Compartment Syndromes (PubMed ID:15181952)
19. Coronary Restenosis (PubMed ID:15215483)
20. Dementia (PubMed ID:14558247)
21. Demyelinating Diseases (PubMed ID:16530131)
22. Depressive Disorder (PubMed ID:18291301)
23. Diabetic Neuropathies (PubMed ID:4776668)
24. Dizziness (PubMed ID:5572387)
25. Drug Eruptions (PubMed ID:11792017)
26. Drug Hypersensitivity (PubMed ID:5572387)
27. Dyspnea (PubMed ID:5572387)
28. Epilepsy (PubMed ID:4169978)
29. Eye Diseases (PubMed ID:4159602)
30. Headache (PubMed ID:5572387)
31. Heart Defects, Congenital (PubMed ID:17124548)
32. Heart Diseases (PubMed ID:22166485)
33. Hematologic Diseases (PubMed ID:17721351)
34. Hemolytic-Uremic Syndrome (PubMed ID:7842113)
35. Homocystinuria (PubMed ID:2044594)
36. Hyperhomocysteinemia (PubMed ID:12598836)
37. Imerslund-Grasbeck syndrome (PubMed ID:10719679)
38. Leukoencephalopathies (PubMed ID:12749323)
39. Liver Diseases (PubMed ID:6533326)
40. Liver Neoplasms, Experimental (PubMed ID:199903)
41. Lupus Erythematosus, Systemic (PubMed ID:17718048)
42. Malabsorption Syndromes (PubMed ID:20152742)
43. Muscle Weakness (PubMed ID:2044594)
44. Muscular Atrophy (PubMed ID:2044594)
45. Myelitis, Transverse (PubMed ID:11965427)
46. Myocardial Infarction (PubMed ID:17412321)
47. Myoclonus (PubMed ID:11182287)
48. Nervous System Diseases (PubMed ID:2044594)
49. Neurocognitive Disorders (PubMed ID:12269601)
50. Peripheral Nervous System Diseases (PubMed ID:16530131)
51. Polyneuropathies (PubMed ID:4776668)
52. Postoperative Complications (PubMed ID:20152742)
53. Psychotic Disorders (PubMed ID:25729574)
54. Renal Insufficiency (PubMed ID:22166485)
55. Rosacea (PubMed ID:11763399)
56. Schizophrenia (PubMed ID:25729574)
57. Scleroderma, Localized (PubMed ID:15355372)
58. Spinal Cord Diseases (PubMed ID:14626725)
59. Subacute Combined Degeneration (PubMed ID:11785055)
60. Thrombosis (PubMed ID:4632789)
61. Urticaria (PubMed ID:11792017)
62. Venous Thromboembolism (PubMed ID:12598836)
63. Vision Disorders (PubMed ID:8220105)
Potential Health Benefits For:
1. Anemia, Macrocytic (PubMed ID:15355372)
2. Atrophy (PubMed ID:23690582)
3. Birth Weight (PubMed ID:29129240)
4. Blood Platelet Disorders (PubMed ID:4632789)
5. Brain Damage, Chronic (PubMed ID:23690582)
6. Cataract (PubMed ID:11438049)
7. Cognition Disorders (PubMed ID:23690582)
8. Drug-Related Side Effects and Adverse Reactions (PubMed ID:24099722)
9. Fatty Liver (PubMed ID:7445574)
10. Fatty Liver, Alcoholic (PubMed ID:20118189)
11. Helicobacter Infections (PubMed ID:11505263)
12. Hypotension, Orthostatic (PubMed ID:2037751)
13. Liver Cirrhosis, Experimental (PubMed ID:18239293)
14. Metabolism, Inborn Errors (PubMed ID:11182287)
15. Neoplasms (PubMed ID:1962580)
16. Neurologic Manifestations (PubMed ID:18291301)
17. Optic Neuritis (PubMed ID:4175520)
18. Pain (PubMed ID:11516431)
19. Pancytopenia (PubMed ID:11182287)
20. Paraparesis (PubMed ID:19821069)
21. Placenta Diseases (PubMed ID:29129240)
22. Psychophysiologic Disorders (PubMed ID:4169978)
23. Sinus Thrombosis, Intracranial (PubMed ID:18786290)
24. Sprue, Tropical (PubMed ID:4951496)
25. Stroke (PubMed ID:16517955)
26. Vitamin B 12 Deficiency (PubMed ID:13082065)
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